Sr. Director, Health Economics and Outcomes Research - Lexington

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Active since 30-10-2018 Job category Science, research & development
Location Lexington Level Manager
Educational level Bachelor / Graduate Employment type -
Hours 40 Salary Competitive
Place in the Organization

uniQure is dedicated to bringing innovative therapies or unmet medical needs to patients. In doing so each function in uniQure is directly or indirectly responsible for the lives of patients. This responsibility should be part of our day-to-day working lives by (i) living up to high quality standards and (ii) by recognizing the sense of urgency in areas of high medical need.

uniQure is currently preparing for a commercial launch of a hemophilia B gene therapy and building its Global Medical Affairs capabilities. This position will be responsible for global Health Economics and Outcomes Research strategy and tactics across uniQure’s pipeline and will serve as the functional lead for HEOR. As the Senior Director, this person will develop strategies to demonstrate the clinical, economic, and humanistic value of uniQure’s products and lead execution of health outcomes research and economics modeling tactics and evidence generation plans, creation of global value dossiers, as well as provide input into clinical trial design to deliver robust market-relevant evidence to support broad and appropriate access to uniQure’s therapies.

Key result areas (major duties, accountabilities and responsibilities):

  • Define the HEOR strategy for uniQure’s hemophilia B gene therapy and subsequent clinical stage assets including Huntington Disease
  • Lead execution of HEOR strategic plans for uniQure’s clinical assets, including studies on burden/cost of illness, real-world outcomes, epidemiology, standard of care, and unmet medical needs
  • Collaborate with Clinical Development to incorporate HEOR perspectives and strategies in the clinical development plan and provide input into clinical protocol design to capture HEOR endpoints relevant to payers, physicians and patients
  • Lead development of health economics models in collaboration with Market Access
  • Develop product value story and work with colleagues across the organization to educate on the value proposition of the company’s products to internal and external stakeholders
  • Prepare global value and reimbursement dossiers and oversee submission to relevant HTAs; support HTA/payer interactions in conjunction with Market Access as needed
  • Manage external vendors and HEOR budget as required to achieve deliverables
  • Understand HTA/payer requirements globally and actively monitor the changing global health care landscape to anticipate future resource needs of internal and external stakeholders and prepare the organization
  • Serve as HEOR subject matter expert in cross-functional teams; provide methodological & analytical expertise regarding the utilization of real-world data.
  • Develop HEOR publications for dissemination in appropriate scientific congresses and peer reviewed journals in alignment with program publication strategy

Qualifications & Skills:

  • Advanced degree (PhD, MS/MPH, or PharmD) in a health economics, epidemiology, health services research, public health, scientific discipline, or related fields.
  • 5-10 years of experience in HEOR and/or market access in the pharmaceutical/biotechnology industry; experience in rare disease strongly preferred
  • Demonstrated technical and strategic excellence in designing, conducting, and interpreting health economics and outcomes research, with a particular emphasis on quality of life and other patient-reported outcomes assessments
  • Background in Hemophilia or Huntington’s Disease is a plus, but not required
  • Significant experience with both drug development and marketed products
  • In-depth knowledge and experience in or with a variety of US/EU payer segments, including but not limited to: HTAs, health plans, PBMs, providers, commercial, and government
  • Must be fully cognizant and adhere to all regulatory, legal, and compliance standards for Medical Affairs activities
  • Ability to travel up to 30% of the time, both US and international

Core competencies:

  • Demonstration of an ability to embody uniQure’s values
  • Strong interpersonal skills and demonstrated leadership in working in cross functional environment and influencing management decisions
  • Effective planning, prioritization, management, and organizational skills
  • Ability to navigate ambiguous, complex, and difficult situations
  • Ability to interface with multiple stakeholders, including clinicians and payers
More information
This listing is a full-time job

Job category Science, research & development
Industry / Industries Biotechnology
Region United States
Keywords Medical Affairs

Contact information

Name Jennifer Wagner